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CSIR-Indian Institute of Integrative Medicine

CSIR-Indian Institute of Integrative Medicine

(Council of Scientific & Industrial Research)

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Dr. Buddh Singh

Dr. Buddh Singh

Sr. Technical Officer(II)

Natural Products & Medicinal Chemistry Division

CSIR – Indian Institute of Integrative Medicine,Canal Road, Jammu – 180001
Email: bsingh @iiim.res.in

  • Profile
  • Position Held
  • Area of Expertise
  • Project Involved / Ongoing Projects
  • Publications and Patents
  • Awards / Honours
  • Group

Profile

Bio Sketch

Born on first July 1966 in a small village Gwalikhera Uttar Paradesh. Schooling was done at A.V. Inter college Tera Meerut. Postgraduate and graduation was done from Janta Vedic College Baraut U.P.  Started carrier as Technical Assistant from 1994 currently working as Sr. Technical officer (II) in Bio Organic Chemistry Division Doctor of philosophy (Ph.D) title “CHEMO ENZYMATIC PREPATION OF BIO MOLECULES “completed in 2013  under the guidance  of Dr.  S.C. Taneja and Dr. Shiromani Sharma  with D.N college Meerut affiliated with  Chaudhary Charan Singh University Meerut (U.P) and CSIR IIIM Jammu

Buddh Singh have more than 25 years research experience in both synthetic as well as natural products chemistry.

Education

Degree Subjects University Qualifying Year
Ph.D. Organic Chemistry Chaudhary Charan Singh University Meerut (U.P) 2013
M.Sc Organic Chemistry Chaudhary Charan Singh University Meerut (U.P) 1988

 

B. Sc Zoology, Botany, Chemistry Chaudhary Charan Singh University Meerut (U.P) 1986
Intermediate Hindi, English, Physics Chemistry Biology Allahabad  board (U.P) 1984
High School Hindi, English, Math, Science, Biology Allahabad  board (U.P) 1982

Position Held

Position Held

Position Held Period Organization
Sr. Technical officer (II) 14-02-2014- Till date CSIR- IIIM Jammu
Sr. Technical officer (I) 14-02-2009-14-02-2014 CSIR-  IIIM Jammu
T.O.A 14-02-2004-14-02-2009 CSIR-  IIIM Jammu
S.T.A. 14-02-1999-14-02-2004 CSIR-  IIIM Jammu
Technical Assistant 15-02-1994-14-02-1999

 

CSIR-  IIIM Jammu

Area of Expertise

Area of Expertise

  • Chemo-enzymatic Studies of biologically active intermediates, Natural Product Chemistry and Synthetic Chemistry.

Project Involved / Ongoing Projects

Projects

Involved in several major project of Institute  eg.

  • Kinetic resolution of S(+) Naproxen
  • Procter & Gamble
  • Development of novel target based anticancer therapeutics (SIP-0027)
  • Preclinical development of NCE leads and botanicals for IND filing. (MLP6008)
  • CSIR Sickle Cell Anaemia mission   HCP-0009
  • CSIR-Phyto-pharmaceutical Mission (HCP0010)
  • Natural Product Chemistry and Pharmacology of Medicinal Plants (MLP-4012)

Publications and Patents

Publications

Authors Title Journal
Opender Koul, J.S.Shankar, NishiMehta, S.N.Sharma, Buddh Singh and S.C.Taneja. Resistance of Insects in selective Ecotypes of Cymbopogon Pendulus (Nees ex Steud) Wats. Pesticide Research Journal (1995)7, 2, 132-139.

 

 

 

S. Koul, B. Singh, S. C. Taneja* and G. N. Qazi.

 

New chemo and chemo-enzymatic synthesis of β-benzyl-γ-butyrolactones. Tetrahedron (2003) 59, 3487–3491.
Surrinder Koul, Jawahir Lal Koul, Buddh Singh, Munish Kapoor, Rajinder Parshad,Kuldeep S. Manhas, Subhash C. Taneja* and Ghulam N. Qazi

 

Trichosporon beigelli esterase (TBE): a versatile esterase for the resolution of economically important racemates Tetrahedron: Asymmetry (2005) 16, 15, 2575–2591.
Buddh Singh, Pankaj Gupta, Asha Chaubey, Rajinder Parshad , Shiromani Sharma , Subhash C. Taneja .*

 

Enantiomerically pure a-methoxyaryl acetaldehydes as versatile precursors: a facile chemo-enzymatic methodology for their preparation Tetrahedron: Asymmetry (2008)19, 22, 2579–2588.
Alamgir A. Dar, Santosh K. Rath, Afnan Qaudri, Buddh Singh, Sheikh A. Tasduq, Anil Kumar, Payare L. Sangwan,

 

Isolation, cytotoxic evaluation, and simultaneous quantification of eight bioactive secondary metabolites from Cicer microphyllum by high-performance thin-layer chromatography .  J. Sep. Sci. (2015) 38, 4021–4028
Imran Khan, Santosh K. Guru, Santosh K. Rath,  Praveen K. Chinthakindi ,

Buddh Singh, Surrinder Koul , Shashi Bhushan , Payare L. Sangwan

A novel triazole derivative of betulinic acid induces extrinsic and intrinsic apoptosis in human leukemia HL-60 cells. European Journal of Medicinal Chemistry (2016) 108, 104–116.
Buddh Singh, Shiromani Sharma, Subhash C. Taneja, Ravi Shankar, and Payare L. Sangwan.

 

β-(Methoxy-(substitutedphenyl)-methyl)-γ-butyrolactones:

A short synthesis from cinnamyl acetate.

 

SYNTHETIC COMMUNICATIONS (2016) 46, 4, 361–366

Patents

Inventors/ Contributors Title Description Year
S. Koul, B. Singh, S. C. Taneja* and G. N. Qazi.

 

New chemo and chemo-enzymatic synthesis of β-benzyl-γ-butyrolactones. NF-463/2001 Dell No-0210 Dell/2003 USP-7153983 Dated 26-12-2006
 S.Koul, M.V.Reddy, P.L.Sangwan, Buddh Singh, Kumar.Ch. Parveen, Inshad aliKhan, Nitin Pal Kalia, Amit Nargotra , Ram Vishwakarma.

 

Novel diamide as potentiators of the bio efficiency of drugs. NF- 0042/2011 , 0864DEL2011  

Awards / Honours

Awards and Honours

NIL

Group

Students

NIL

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