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CSIR-Indian Institute of Integrative Medicine

CSIR-Indian Institute of Integrative Medicine

(Council of Scientific & Industrial Research)

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Dr. Amol B. Gade

Dr. Amol B. Gade

Scientist

Natural Products & Medicinal Chemistry Division

CSIR – Indian Institute of Integrative Medicine, Canal Road, Jammu – 180001
Email: amolgade[dot]iiim[at]csir[dot]res[dot]in

  • Profile
  • Position Held
  • Area of Expertise
  • Project Involved / Ongoing Projects
  • Publications and Patents
  • Awards / Honours
  • Group

Profile

Bio Sketch

Dr. Amol B. Gade is a Scientist at the CSIR–Indian Institute of Integrative Medicine (CSIR–IIIM), Jammu. He completed his Ph.D. in Chemical Sciences under the supervision of Dr. Nitin T. Patil from AcSIR–CSIR–National Chemical Laboratory, Pune in 2018, and later pursued postdoctoral research at the University of Louisville, USA. Prior to joining CSIR–IIIM, he acquired extensive experience in process development and scale-up while working with leading pharmaceutical companies.

At CSIR–IIIM, his research focuses on developing efficient and scalable synthetic routes for APIs and pharmaceutical intermediates. His group is particularly interested in micellar catalysis and iron-catalyzed transformations that align with the principles of green chemistry. The team works on improving synthetic efficiency, minimizing environmental impact, and exploring new routes to bioactive molecules using mechanistic insights and modern synthetic tools.

Education

Degree Subjects University Qualifying Year
PhD Chemical Sciences CSIR-National Chemical Laboratory, Pune, India 2018
MSc Organic Chemistry University of Pune, India 2012
BSc Chemistry University of Pune, India 2010

Position Held

Position Held

Position Held Period Organization
Scientist 2022- Present Natural Products & Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Jammu, India
Senior Research Investigator 2021-2022 Syngene International Limited, Hyderabad, India.
Research Scientist 2019-2021 Piramal Pharma Limited, Ahmedabad, Gujrat, India
Post-doctoral Associate 2018-2019 University of Louisville, KY (USA)
Research Associate 2012-2013 Syngenta Biosciences Pvt. Ltd. Goa, India

Area of Expertise

Area of Expertise

  • Route Scouting and Process Development
  • Sustainable Organic Synthesis
  • Asymmetric Catalysis

 
 
 
 
 
 
 
 

Project Involved / Ongoing Projects

Projects

  • Active Pharmaceutical Ingredients for Affordable Health Care (API–AHC)
  • Discovery & Pre-clinical Development of Antivirals for COVID-19
  • SERB-SRG: Iron-Catalyzed Late-Stage C-H Oxygenation of Arenes

 
 
 
 
 
 
 
 

Publications and Patents

Publications

Authors Title Journal
Maryam Nabi, Kirti Sharma, Raj S. Wandre and Amol B. Gade* One-pot oximation-Beckmann rearrangement under mild, aqueous micellar conditions Green Chem., 2025, 27, 5332.
Amol B. Gade,* Urvashi and Nitin T. Patil* Asymmetric gold catalysis enabled by specially designed ligands Org. Chem. Front., 2024, 11, 1858.
Uyen T. Duong, Amol B. Gade, Scott Plummer, Fabrice Gallou, and Sachin Handa* Reactivity of Carbenes in Aqueous Nanomicelles Containing Palladium Nanoparticles ACS Catal., 2019, 12, 10963.
Pradip N. Bagle, Manoj V. Mane, Shashank P. Sancheti, Amol B. Gade, Samir R. Shaikh, Mu-Hyun Baik*, and Nitin T. Patil* Gold(I)-CatalyzedHydroxy Group Assisted C(sp2)–H Alkylation of Enaminones with Diazo Compounds To Access 3-Alkyl Chromones Org. Lett., 2019, 21, 335.
Ravindra D. Mule, Aslam C. Shaikh, Amol B. Gade, Nitin T. Patil* A new class of N-doped ionic PAHs via intramolecular [4+2]-cycloaddition between arylpyridines and alkynes Chem. Commun., 2018, 54, 11909.
Amol B. Gade, Pradip N. Bagle, Popat S. Shinde, Vipin Bhardwaj, Subhrashis Banerjee, AjitChande, Nitin T. Patil* Catalytic Enantioselective 1,3-Alkyl Shift in Alkyl Aryl Ethers: Efficient Synthesis of Optically Active 3,3′-Diaryloxindoles Angew. Chem. Int. Ed., 2018, 57, 5735.
Amol B. Gade, Nitin T. Patil* Catalytic Enantioselective Aza-Piancatelli Rearrangement Synlett, 2017, 28, 1096.
IndradweepChakrabarty, Suleman M. Inamdar, Manjur O. Akram, Amol B. Gade, Subhrashis Banerjee, SaibalBera, Nitin T. Patil* [3+2]-Annulation of Platinum-Bound AzomethineYlides with Distal C=C Bonds of N-Allenamides Chem. Commun., 2017, 53, 196.
Amol B. Gade, Nitin T. Patil* Gold(I)-Catalyzed Hydroaminaloxylation and Petasis−Ferrier Rearrangement Cascade of Aminaloalkynes Org. Lett., 2016, 18, 1844.

Patents

Inventors/ Contributors Title Description Year
Amol B. Gade, Ahemad M. Pathan, Raj S. Wandre,Zabeer Ahmed A Process for the Preparation of Lenalidomide and Intermediates Thereof IN202411100693 Filing Date

18-Dec-2024

Maryam Nabi, Raj S. Wandre, Yogesh Sardana, Alna K. Martin, Gunjan Lakhanpal, Bokara K. Kumar, Amit Nargotra, Qazi N. Ahmed, Amol B. Gade, Zabeer Ahmed Pyridine-3-yl quinolin-2(1H)-one Derivatives as Anti-Viral Agent IN202411101808 Filing Date

20-Dec-2024

Awards / Honours

Awards and Honours

  • Spotlight, Shining Star and Super Achievers recognitions by Piramal Pharma Limited
  • Post doctoral fellowhip by University of Louisville, KY
  • Best Poster Prize in organic chemistry for 2016 by NCL research foundation at CSIR-National Chemical Laboratory, Pune
  • CSIR-UGC NET-JRF (Chemical Sciences)

 
 
 
 
 
 
 

Group

Students

Photo Name Area of Interest Position
Maryam Nabi Sustainable Organic Synthesis Project Associate-I
Raj S. Wandre C-H Oxygenation of Arenes Project Associate-I
Kirti Sharma Sustainable Organic Synthesis Project Associate-I
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