• Identification of novel chemical scaffolds and drug targets for anti-tuberculosis, anti-bacterial, anti-protozoan and anti-viral activity.
• Establishing new drug discovery platforms for high throughput screen for finding new and potent drugs against the resistant strains of bacterial pathogens.

• Screening of chemical libraries for identification of novel chemical scaffold as anti-infective agent.
• Identification and characterization of novel drug target for drug discovery.
• Assay development

Biosafety Level-3 facility

Clinical Microbiology Division encompasses a State-of-the-art Biosafety Level-3 (BSL-3) facility for handling and experimentation with hazard group III pathogens. The facility fully complies with the Biosafety in Microbiological and Biomedical Laboratories (BMBL) guidelines. This facility consists of two in-vitro experimentation labs and one animal handling (mice & guinea pigs) for in-vivo experimentations.

The facility is fully equipped with Biosafety cabinets, incubators, centrifuges, deep freezers, CO2 incubators and has two double door autoclaves for handlings of the hazardous waste generated while working on pathogens.

Molecular Biology

The facility is well equipped with PCR machines, Real-Time PCR, Electrophoresis systems, Gel Documentation systems, Gene pulsar and other such lab equipment for molecular biology work. PCR amplification, gene cloning, native enzyme purification and differential gene expression are some of the experimentations routinely performed in this facility. Magnetic stirrers with heating blocks and microscope were purchased under (GAP3106) project sponsored by DBT.

Anti-infective research facility

We are actively working on plant based and synthetic pharmacophores with anti-infective activity against M. tuberculosis, L. donovani, gram negative and gram-positive bacteria. A large collection of bacterial, fungal, protozoan and M. tuberculosis clinical isolates is available for extensive evaluation of compounds.

• Development of Nutraceutical Products from Algae
• Understanding the physiological role of forskolin in Coleus forskohlii
• Deciphering the mechanism(s) of host-endophytes coevolution, enhanced secondary metabolite production and crop productivity
• Testing of 2019 novel coronavirus (2019-nCoV) in human clinical samples