Dr. J S Momo Hmungshel A.

Dr. J S Momo Hmungshel A.

Scientist

Natural Products & Medicinal Chemistry Division

CSIR – Indian Institute of Integrative Medicine, Canal Road, Jammu – 180001
Email: hmunshel[dot]jasha[at]iiim[dot]res[dot]in

Profile

Bio Sketch

Jasha Momo Hmungshel, Ph.D., MRSC, received his Bachelor of Science in Chemistry (Honours) with Biochemistry & Zoology (Elective) in 2005 at St. Edmund’s College, Shillong, India, and Master of Science in Chemistry (Organic Chemistry), in 2007, from North-Eastern Hill University, Shillong, India. He completed his Ph.D. in Natural Product Chemistry from the Department of Chemistry, North Eastern Hill University, Shillong, India 2016. He worked as STA in the Sophisticated Analytical Instrument Facility (SAIF), North Eastern Hill University, Shillong, Meghalaya, India, before joining the Natural Products & Medicinal Chemistry (NPMC) Division, CSIR-IIIM, at Jammu. His research interests are the Chemistry of Natural Products, Organic Synthesis, Chemical Biology, and Enzymatic reactions. He also has a keen interest in networking Science with Society. He believes in curiosity-driven Chemistry and Science. He was previously involved with the International Younger Chemist Network (IYCN) and the Global Youth Biodiversity Network (GYBN). He has a life membership of the Chemical Research Society of India (CRSI), The Biotech Research Society, India (BRSI), and the Electron Microscope Society of India (EMSI); he is the Member of the American Chemical Society (ACS), and the Royal Society of Chemistry (RSC).

Education

Degree Subjects University Qualifying Year
PhD Natural Product Chemistry North Eastern Hill University (NEHU), Shillong, India 2016
M.Sc. Chemistry/Organic Chemistry  NEHU, Shillong, India 2007
BSc. (Hons.) Chemistry (Hons.), Biochemistry, Zoology NEHU, Shillong, India 2005

Position Held

Position Held

Position Held Period Organization
Scientist 30.07.2020-till date CSIR-IIIM, Jammu
STA 30th November, 2011-21st July, 2020 Sophisticated Analytical Instrument Facility, North Eastern Hill University, Shillong – 793022,

Meghalaya, India

 

 

Area of Expertise

Area of Expertise

  • Natural Product Isolation & Purification Techniques| Organic synthesis |Chemical Modifications of Natural Products | Application of Hyphenated Techniques in Natural Product-based Drug Development

Project Involved / Ongoing Projects

Projects

Ongoing Project Funding Agency Role
Diving into the deep ocean sea mounts for biodiversity, ecosystem functioning, and mining of genetically encoded metabolites (GEMs) using a Combined OMICS approach

 

 Ministry of Earth Science, Govt. of India, New Delhi Co-PI & Project In-charge, CSIR-IIIM, Jammu
Optimization of ursolic content in Lavender Marc and its semi-derivatives for anti­ inflammatory and anti-arthritic potential funded

 

 CSIR, New Delhi  PI
Phytopharmaceutical Development of Ficus semicordata Buch. -Ham. Ex Sm. as per regulatory guidelines of DCGI (under the phytopharmaceutical Mission for North East Region) [GAP2180]

 

 DBT, New Delhi Co-ordinator & PI
CSIR-Aroma Mission Phase 2 & 3 (HCP-007)

 

 CSIR, New Delhi Co-PI
High-End workshop (KARYASHALA) on Hands-on Workshop on Advance Techniques in Natural Products & Medicinal Chemistry (2021-2022)

 

 SERB, DST, New Delhi Event Organiser

Publications and Patents

Publications

Authors Title Journal
Kumar, Puneet, Sapna Saini, Anjali Gangwar, Rashmi Sharma, and Jasha Momo H. Anal* Antibacterial activity of structurally diverse natural prenylated isobavachalcone derivatives RSC Advances 14, no. 45 (2024): 32771-32785.
Shahi, Ashutosh, Rakshit Manhas, Srija Bhattacharya, Arti Rathore, Puneet Kumar, Jayanta Samanta, Manish Kumar Sharma, Avisek Mahapa, Prasoon Gupta, and Jasha Momo H. Anal* Synthesis and antibacterial potential of novel thymol derivatives against methicillin-resistant Staphylococcus aureus and P. aeruginosa pathogenic bacteria Frontiers in Chemistry 12 (2024): 1482852.
Vanlalveni, Chhangte, Vanlalhruaii Ralte, Hlawncheu Zohmingliana, Shikhasmita Das, Jasha Momo H. Anal, Samuel Lallianrawna, and Samuel Lalthazuala Rokhum. A review of microbes mediated biosynthesis of silver nanoparticles and their enhanced antimicrobial activities.  Heliyon 10, no. 11, e32333 (2024).
Lone, Waseem Iqbal, Jagdish Chand, Puneet Kumar, Yashi Garg, Zabeer Ahmed, Debaraj Mukherjee, Anindya Goswami, and Jasha Momo H. Anãl* Discovery of colchicine aryne cycloadduct as a potent molecule for the abrogation of epithelial to mesenchymal transition via modulating cell cycle regulatory CDK-2 and CDK-4 kinases in breast cancer cells Bioorganic Chemistry, Volume 150 (2024): 107581.
Kumar, Puneet, Ruhi Singh, Deepak Sharma, Qazi Parvaiz Hassan, Boobalan Gopu, and Jasha Momo H. Anal* Design, synthesis, and biological evaluation of chalcone acetamide derivatives against triple-negative breast cancer. Bioorganic & Medicinal Chemistry Letters 107 (2024): 129795.
Hlawncheu Zohmingliana, Joseph V. L. Ruatpuia, Jasha Momo H. Anal, Feng Chai, Gopinath Halder, Amarajothi Dhakshinamoorthy Metal-Organic Framework-Derived Solid Catalyst for Biodiesel Production from Jatropha curcas Oil: Kinetic Study and Process Optimization Using Response Surface Methodology International Journal of Energy Research, vol. 2024, Article ID 6336617, pp.1-16 (2024). https://doi.org/10.1155/2024/6336617
Kyndiah L, Sarkar FK, Gajurel S, Sarkar R, Jasha Momo H. Anal,  AK Pal Pd@GO catalyzed stereo- and regio-selective addition of arenes to alkynes and synthesis of coumarins via C–H functionalization Org. Biomol. Chem., 21, 7928-7934 (2023). https://doi.org/10.1039/D3OB01237A
Mohd Hassan, Jasha Momo H. Anal, Ravail Singh Comprehensive analysis of codon usage pattern in Eisenia fetida and its correlation with gene expression Biocatal. Agric. Biotechnol.,52, 102810 (2023). https://doi.org/10.1016/j.bcab.2023.102810.
Das, Shikhasmita, Jasha Momo H. Anal, Pranjal Kalita, Lakshi Saikia, and Samuel Lalthazuala Rokhum. Process optimization of biodiesel production using waste snail shell as a highly active nanocatalyst International Journal of Energy Research 2023, no. 1 (2023): 6676844.
Samridhi Sharma, Monu Kumar Shukla, Krishan Chander Sharma, Tirath, Lokender Kumar,

Jasha Momo H. Anal, Santosh Kumar Upadhyay, Sanjib Bhattacharyya, Deepak Kumar

 Revisiting the therapeutic potential of gingerols against different pharmacological activities Naunyn-Schmiedeberg’s Archives of Pharmacology. Naunyn-Schmiedeberg’s Arch Pharmacol (2022). https://doi.org/10.1007/s00210-022-02372-7
Gouda, S.P.; Jasha Momo H. Anal; Kumar, P.; Dhakshinamoorthy, A.; Rashid, U.;  S.L.Rokhum Microwave-Assisted Biodiesel Production Using UiO-66 MOF Derived Nanocatalyst: Process Optimization Using Response Surface Methodology Catalysts 2022, 12, 1312. https://doi.org/10.3390/catal12111312.
Fillip Kumar Sarkar, Ajay Gupta, Ramen Jamatia, Jasha Momo H Anal, Amarta Kumar Pal A green and sustainable approach for the synthesis of 1, 5-benzodiazepines and spirooxindoles in one pot using a MIL-101 (Cr) metal-organic framework as a reusable catalyst New Journal of Chemistry, 45, pp.19553-19564 (2021).
Bishwajit Changmai, Gunindra Pathak, Jasha Momo H Anal, and Lalthazuala Rokhum Heterogeneous system in organic synthesis. Mini-Reviews in Organic Chemistry, Volume 17; pp.740 – 753 (2020);

 
Jasha Momo H. Anal, O. Sanentiba Ozukum, S. Willson Monsang, Ghanashyam Bez Donkupar Syiem. Comparison of the cyclic voltammetry (CV) and bio-assays for the determination of antioxidant Capacity from different extracts of Potentilla fulgens L… L.

 

 Trends in Experimental BIOLOGY, Volume 3, pp.50-60 (2018).
Diparjun Das, Gunindra Pathak, Jasha Momo H. Anal, Lalthazuala Rokhum Polymer Supported Triphenylphosphine-Methylacrylate Complex: An Efficient Catalyst for the Selective Iodination of Alcohols. Current Applied Polymer Science, 2017, 1, 63-71.

 
Diparjun Das, Jasha Momo H Anal and Lalthazuala Rokhum A mild and highly Chemoselective iodination of alcohol using polymer supported DMAP

 

 Journal of Chemical Science, Vol. 128, No. 11, pp. 1695–170 (2016).
Jasha Momo H. Anal and Petevino Chase  Trace elements analysis in some medicinal plants using Graphite Furnace-Atomic Absorption Spectroscopy.

 

 Environmental Engineering Research, 21(3): pp.247-255(2016).
Jasha Momo H. Anal, Rabiya Majeed, Ghanashyam Bez, Donkupar Syiem, Abid Hamid and Ajit K. Saxena   In vitro cytotoxicity of the polar extracts of Potentilla fulgens L. against human cancer cell lines: Detection and isolation of bioactive phenolics.

 

 Journal of Chemical and Pharmaceutical Research, 6(9): pp.89-95(2014).
E. Dkhar, Paul S. Dkhar, and Jasha Momo H. Anal Trace Elements Analysis in Drinking Water of Meghalaya by Using Graphite Furnace-Atomic Absorption Spectroscopy and in relation to Environmental and Health Issues.

 

 Journal of Chemistry Volume 2014, Article ID 975810, http://dx.doi.org/10.1155/2014/975810.
Jasha Momo H. Anal Trace and Essential Elements Analysis in Cymbopogon citrates (DC.) Stapf Samples by Graphite Furnace-Atomic Absorption Spectroscopy and Its Health Concern.

 

 Journal of Toxicology, Article ID 690758, Volume 2014, http://dx.doi.org/10.1155/2014/690758.

 
Pranjal P. Bora, Ghanashyam Bez, Jasha Momo H. Anal First example of hydrolytic kinetic resolution of acrylate of secondary alcohols by lipase Amano AK.

 

 Journal of Molecular Catalysis B: Enzymatic 72, pp. 270– 275.

Patents

  • Process for Producing Fermented Turmeric and Formulation with Selaginella Bryopteris using Fermentation [Indian Patent file]

Awards / Honours

Awards and Honours

Memberships:

  • Annual Member, Indian Science Congress Association, Kolkata, India.
  • Life Member, Electron Microscopy Society of India, Kolkata, India.
  • Affiliate Member, International Union of Pure and Applied Chemistry (IUPAC).
  • Member, Royal Society of Chemistry (RSC), London.
  • Member, Sub-committee, Conference Presence Committee, International Younger Chemist Network (IYCN).
  • Member, American Chemical Society (ACS), Washington, D.C.

Awards and Distinctions:

  • IUPAC Travel grant to attended IUPAC General Assembly & Conference, Paris, 2019
  • DST-SERB Young Scientist International Travel Scheme (ITS) Grant by Department of Science and Technology (DST), Govt. of India (2012).
  • DST-FIST-NER visiting fellowship to Ph.D. student by Department of Science and Technology (DST), Govt. of India (2010-2011).
  • Graduate Aptitude Test in Engineering (GATE) qualified in Chemical Sciences, March, 2009 conducted by IIT, Roorkee.

Group

Students

Photo Name Area of Interest Position
PUNEET KUMAR

 

 Extraction, isolation and purification of natural products and semi-synthetic modification of natural products AcSIR PhD Scholar/ Project Associate-I (CSIR-Aroma Mission 2.0)
Deepak Sharma

M. Sc in Organic Chemistry

(Cluster University of Jammu)

 Optimization of extraction & isolation of Bioactive Natural Products Project Associate-I (CSIR SEED Grant)
Shubh Laxmi

M.Pharm (Medicinal Chemistry, Banasthali Vidyapeeth, Rajasthan)

 Value addition & formulation  of Natural Products Project Associate-I (CSIR AROMA Mission Phase 3)
Ashwini Bonsade

M.  S Pharma Natural Product (NIPER, Ahmedabad)

 Extraction & isolation of Bioactive Natural Products Project Associate-I (DOM project funded by Ministry of Earth Sciences)

PhD Positions Available:

PhD positions are available for CSIR/UGC-NET Fellowships and DST-INSPIRE Fellows. They are highly motivated or curiosity-driven candidates for venturing into the Chemistry of Natural Products/Medicinal Chemistry/Chemical Biology. Foreign candidates can also apply through CSIR-TWAS fellowships.
Postdoctoral positions are available for PDF or any other funded postdoctoral fellowships.
Interested candidates are encouraged to send their CVs directly to the following email ID: hmunshel.jasha@iiim.res.in.