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Dr. Bhahwal Ali Shah
Principal Scientist
Natural Products & Medicinal Chemistry Division
CSIR – Indian Institute of Integrative Medicine,Canal Road, Jammu – 180001
Email: bashah[at]iiim[dot]res[dot]in
Bio Sketch
Bhahwal Ali Shah is a Principal Scientist at CSIR-Indian Institute of Integrative Medicine, Jammu. His research interests include Natural Product Chemistry, Medicinal Chemistry and the Development of New Synthetic Methods using Photoredox Catalysis. He has been instrumental in establishing and the Microbial Natural Product Chemistry facility at CSIR-IIIM, Jammu. He has more than 15 years of research experience with over 100 publications in international journals of repute. Dr Bhahwal also received the prestigious CSIR Young Scientist Award in Chemical Sciences 2015 and NASI-Platinum Jubilee Young Scientist Award in Chemical Sciences 2016.
Education
| Degree | Subjects | University | Qualifying Year |
| Ph. D. | Chemical Science | Guru Nanak Dev University, Amritsar | 2009 |
| M. Sc. | Chemistry | Ch. Charan Singh University, Meerut, UP | 2004 |
| B. Sc. | Chemistry, Zoology, Botany, English | Govt. Gandhi Memorial Science College, University of Jammu, Jammu | 2002 |
Position Held
| Position Held | Period | Organization |
| Principal Scientist | 04-2019 to Present | CSIR-Indian institute of Integrative Medicine, Canal Road, Jammu |
| Sr. Scientist | 04-2015 to 04-2019 | CSIR-Indian institute of Integrative Medicine, Canal Road, Jammu |
| Scientist | 04-2011 to 04-2015 | CSIR-Indian institute of Integrative Medicine, Canal Road, Jammu |
| Jr. scientist | 04-2008 to 04-2011 | CSIR-Indian institute of Integrative Medicine, Canal Road, Jammu |
Area of Expertise
Research Area
Projects
- Design and Synthesis of Mupirocin Analogues as New Antibacterial Agents [2018-21].[completed]
- Isolation Synthesis of Bioactive Molecules from Microbial Sources [2016-21]. [completed]
- Process Development for COVID-19 API’s: [2020-21] [completed]
- Discovery and Pre-clinical development of Anti-virals for COVID-19 and other diseases (HCP-041) ( 2022-23) [completed}
- Exploration of Photoredox Generated Vinyl Radicals as Precursors to Bio-relevant Scaffolds (GAP-3112) [ongoing].
Publications
Selected publications:
1. Bhat, M.S.; Ganie, M.A.; Kumar, S.; Rizvi, M.A.; Raheem,S.; Shah, B.A.* Visible light mediated synthesis of thioesters using thiocarboxyllic acid as a dual reagent. J. Org. Chem., 2024, https://doi.org/10.1021/acs.joc.3c02877.
2. Ganie, M.A.; Fayaz, F.; Bhat, M.S.; Rizvi, M.A.; Raheem,S.; Shah, B.A.* Visible-Light-Mediated Synthesis of N-Acyl-N,O-hemiacetals from Terminal Alkynes: Access to N,N-N,S-, and N,O-Acetals. Org. Lett., 2023, 8234−8239.
3. Bhat, M. S.; Ganie, M. A.; Shah, B. A.* Metal-Free Tunable 1,2-Difunctionalization of Terminal Alkynes: Synthesis of β-Substituted α,β-Unsaturated Ketones. Chem.Eur.J., 2023, e202302294.
4. Ganie, M.A.; Bhat, M.S.; Rizvi, M.A.; Raheem, S.; Shah, B. A.* Synthesis of 1,2-oxazetidines with a free –NH group via photoredox catalysis. Chem Commun., 2022, 58, 8508-8511.
5. Bhat, M.S.; Ganie, M.A.; Rizvi, M.A.; Raheem, S.; Shah, B. A.*. Photoredox Catalyzed Thioformylation of Terminal Alkynes Using Nitromethane as a Formyl Source. Org. Lett., 2022, 24, 6658-6663
6. Ganie, M.A.; Bhat, M.S.; Rizvi, M.A.; Raheem, S.; Shah, B. A.*. Photoredox-Promoted Selective Synthesis of C-5 Thiolated 2-Aminothiazoles from Terminal Alkynes. Org. Lett.,, 2022, 24, 7757-7762
7. Kumar, S.; Kumar, J.; Naqvi, T.; Raheem, S.; Rizvi,M.A.; Shah, B. A.*.Synthesis of (E)-β-Iodovinyl Sulfones via Photoredox Catalyzed Difunctionalization of Terminal Alkynes. ChemPhotoChem, 2022, 6, e202200110
8. Chalotra,N.; Kumar, J.; Naqvi, T.; Shah, B. A.*.Photocatalytic functionalizations of alkynes. Chem. Commun, 2021, 57, 11285-11300
9. Kumar, J.; Ahmad, A.; Rizvi, M. A.; Ganie, M. A.; Khajuria, C.; Shah, B. A.*. Photoredox-Mediated Synthesis of Functionalized Sulfoxides from Terminal Alkynes. Org. Lett., 2020, 22, 5661-5665
10. Chalotra, N.; Rizvi, M. A.; Shah, B. A.* Photoredox-Mediated Generation of gem-Difunctionalized Ketones: Synthesis of α,α-Aminothioketones. Org. Lett., 2019, 21, 4793-4797
11. Sultan, S.; Bhat, M.-u.-S.; Rizvi, M. A.; Shah, B. A.* Visible Light-Mediated [2 + 2] Cycloaddition Reactions of 1,4-Quinones and Terminal Alkynes. J. Org. Chem., 2019, 84, 8948-8958.
12. Chalotra, N.; Ahmed, A.; Rizvi, M. A.; Hussain, Z.; Ahmed, Q. N.; Shah, B. A.* Photoredox Generated Vinyl Radicals: Synthesis of Bisindoles and β-Carbolines. J. Org. Chem., 2018, 83, 14443-14456.
13. Sultan, S.; Rizvi, M. A.; Kumar, J.; Shah, B. A.* Acyl Radicals from Terminal Alkynes: Photoredox-Catalyzed Acylation of Heteroarenes. Chem.Eur. J., 2018, 24, 10617-10620.
14. Devari, S.; Shah, B. A.* Visible light-promoted C–H functionalization of ethers and electron-deficient arenes. Chem. Commun. 2016, 52, 1490-1493.
15. Kumar, A.; Shah, B. A. Synthesis of Biaryls via Benzylic C–C Bond Cleavage of Styrenes and Benzyl Alcohols. Org. Lett., 2015, 17, 5232-5235.
16. Devari, S.; Kumar, A.; Deshidi, R.; Shah, B. A. C–H functionalization of terminal alkynes towards stereospecific synthesis of (E) or (Z) 2-methylthio-1,4-ene-diones. Chem. Commun., 2015, 51, 5013-5016.
Awards and Honours
- NASI Platinum Jubilee Young Scientist Award in Chemical Sciences 2016
- CSIR Young Scientist Award in Chemical Sciences 2015.
- INDO-US Research Science and Technology Forum Fellowship for the year 2011.
- BOYSCAST Fellowship for the year 2011
- Fast Track Research Grant by DST (2010)
Students
| Photo | Name | Area of Interest | Position |
 |
Dr. Ghazala Khanum (NPDF) | ||
 |
Faheem Fayaz | ||
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Majid Ahmad Ganie | Photoredox Functionalization of Heterocyclic Compounds | Research Fellow Natural Product Chemistry Division CSIR-JRF, GATE, SET M.Sc Chemistry, University of Kashmir. e-mail: ganiemajid7@gmail.com |
 |
Muneer-ul-Shafi Bhat | Photoredox Functionalization of Natural Products | Project Fellow Natural Product Chemistry Division. GATE M.Sc Chemistry, Jamia Hamdard University, Delhi e-mail: munnerbhat442@gmail.com |
 |
Iftkhar Hussain Shah | Developments of new cross- coupling methods using Metallaphotoredox catalysis | Research Fellow Natural Product Chemistry Division. CSIR-JRF M.Sc Chemistry, Aligarh Muslim University. e-mail: naqviiftkhar647@gmail.com |
 |
Sourav Kumar | Development of Novel Photoredox C-H activation strategies | Research Fellow Natural Product Chemistry Division. CSIR-JRF M.sc(Hons.) Chemistry, Guru Nanak Dev University, Amritsar. e-mail: coolsourav418@gmail.com |
ALUMNI:
- Manjeet Kumar
- Renu Chib
- Simmi Sharma
- Arvind Kumar
- Shekariah Devari
- Ramesh Deshidi
- Shaista Sultan
- Farah Manzer
- Neha Chalotra
- Jaswant Kumar
- Aijaz Ahmad (NPDF)