Publications during 2014

1
A general metal free approach to a-ketoamides via oxidative amidation–diketonization of terminal alkynes. Chemical Communications, 2014, 50, 9533-9535.
2
Inhibition of phosphotidylinositol-3 kinase pathway by a novel naphthol derivative of betulinic acid induces cell cycle arrest and apoptosis in cancer cells of different origin.Cell death and Disease, 2014 5(10): e1459.
3
Copper-catalyzed sequential N-arylation of C-amino-NH-azoles. Chemical Communications, 2014, 50, 12911-12914.
4
Molecular characterization of two A-type P450s, WsCYP98A and WsCYP76A from Withania somnifera (L.) Dunal: expression analysis and withanolide accumulation in response to exogenous elicitations. BMC Biotechnology, 2014, 14-89.
5
Biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethyl]-methylamide (CA224), a non-planar analog of fascaplysin inhibits Cdk4 and tubulin polymerization: Evaluation of in vitro and in vivo anticancer activity. Journal of Medicinal Chemistry, 2014, 57, 9658-9672.
6
Synthesis of 2-phenylnaphthalenes from styryl-2-methoxybenzenes. Chemical Communications, 2014, 50, 12076-12079.
7
Pyrano-isochromanones as IL-6 inhibitors: Synthesis, in-vitro and in-vivo anti-arthritic activity. Journal of Medicinal Chemistry, 2014, 57, 7085−7097.
8
Metal-free, high yielding synthesis of unsymmetrical biaryl, bi(heteroaryl), aryl vinyl, aryl alkyl sulfones via coupling of aryne with sulfinic acid salts. RSC Advances, 2014, 4, 50208-50211.
9
HClO4–silica-catalysed regioselective opening of benzylidene acetals and its application towards regioselective HO-4 glycosylation of benzylidene acetals in one-pot. Carbohydrate Research, 2014, 93–96.
10
Intramolecular aglycon delivery for (1 → 2)-β-mannosylation: towards the synthesis of phospholipomannan of Candida albicans. Tetrahedron Letters, 2014, 55, 2945-2947
11
Metal-Free Oxidative Amidation of 2-Oxoaldehydes: A Facile Access to α-Ketoamides. Organic Letters, 2014, 16 (4), 1152–1155.
12
Cloning and functional characterization of three branch point oxidosqualene cyclases from Withania somnifera (L.) Dunal. The Journal of Biological Chemistry, 2014, 289, 17249-17267.
13
Facile access to amides and hydroxamic acids directly from nitroarenes. Organic and Biomolecular Chemistry, 2014, 12, 6465-6469.
14
An inducible NADPH-cytochrome P450 reductase from Picrorhiza kurrooa- an imperative redox partner of cytochrome P450 enzymes. Functional and Integrative genomics, 2014, 14(2), 381-399.
15
C-H Oxygenation and N-Trifluoroacylation of Arylamines Under Metal-Free Conditions: A Convenient Approach to 2-Aminophenols and N-Trifluoroacyl-ortho-aminophenols. Chemistry, 2014, 20(22), 6641-5.
16
Synthesis of 5-substituted-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one analogs and their biological evaluation as anticancer agents: mTOR inhibitors. European Journal of Medicinal Chemistry, 2014, 80, 201-8.
17
A phenylalanine ammonia-lyase ortholog (PkPAL1) from Picrorhiza kurrooa Royle ex. Benth: Molecular cloning, promoter analysis and response to biotic and abiotic elicitors. Gene, 2014, 547(2), 245–256.
18
Trifluoroacetic acid catalyzed thiophenylmethylation and thioalkylmethylation of lactams and phenols via domino three-component reaction in water.RSC Advances,2014, 2014, 4, 14081-14088.
19
Synthesis, antioxidant, neuroprotective and P-glycoprotein induction activity of 4-arylquinoline-2-carboxylates. Organic and Biomolecular Chemistry, 2014, 12, 6267-6277.
20
Click chemistry inspired facile synthesis and bioevaluation of novel triazolyl analogs of Ludartin. Bioorganic & Medicinal Chemistry Letters, 2014, 24(4), 1047-1051.
21
Diversity, molecular phylogeny and bioactive potential of fungal endophytes associated with the Himalayan blue pine (Pinus wallichiana). Microbial Ecology, 2014, 67(4), 877-887.
22
Highly diastereoselective 1,2-dichlorination of glycals using NCS/PPh3: study of substituent and solvent effects. Tetrahedron letters, 2014, 70, 1133-1139.
23
Dysoxylum binectariferum bark as a new source of anticancer drug camptothecin: Bioactivity-guided isolation and LCMS-based quantification. Bioorganic & Medicinal Chemistry Letters, 2014, 24, 3146-3149.
24
Synthesis of non-hydrolysable mimics of glycosylphosphatidylinositol (GPI) anchors. Organic & Biomolecular Chemistry, 2014, 12, 1163-1172.
25
Ligand- and base-free synthesis of phenols by rapid oxidation of arylboronic acids using iron(III) oxide. Tetrahedron letters, 2014, 55, 811–814.
26
C-N bond formation via Cu-catalyzed cross coupling with boronic acids leading to methyl carbazole-3-carboxylate: Synthesis of carbazole alkaloids. RSC Advances, 2014, 4, 4960-4969
27
Synthesis, antileishmanial and antitrypanosomal activities of N-substituted tetrahydro-β-carbolines. Bioorganic & Medicinal Chemistry Letters, 2014, 24, 3247-3250.
28
Capsaicin production by Alternaria alternata, an endophytic fungus from Capsicum annum; LC–ESI–MS/MS analysis, Phytochemistry, 2014, 98, 183–189
29
Anti-inflammatory terpenoids from Boswellia ovalifoliolata. RSC Advances, 2014, 4, 8632-8637
30
Oxidative stress mediated Ca2 release manifests ER stress leading to the UPR in UV-B irradiated human skin cells.Journal of Dermatological Sciences, 2014, 75, 24–35.
31
Cytotoxin and antimicrobial activities of endophytic fungi isolated from Bacopa monnieri (L) pennels (Scrophilariaceae).BMC Complementary and Alternative Medicine, 2014, 14:52.
32
Synthesis, characterization and mechanistic-insight into the anti-proliferative potential of PLGA-gemcitabine conjugate. The International Journal of Pharmaceutics, 2014, 470,51–62.
33
A converent synthesis of alkyne-Azide Cyclo addition derivatives of 4ab-2-propyne podophyllotoxin defecting potent cytotoxic activity.European Journal and Medicinal Chemistry,2014, 77, 47–55.
34
Microwave assisted synthesis a 5-substituted-1H-Pyrazolo [4,3-d] pyrimidine of (6H)-one analogs and their biological evaluation as anticancer agents.European Journal and Medicinal Chemistry,2014,80,201-8.
35
Heterogeneous reusable catalyst ultrasound energy and no solvent : a quick and green receipe for one pot synthesis of B-phosphonomalomtes at room temperature.Tetrahedron Letters ,2014, 55, 623-628.
36
Biodegradable polymeric system for cisplatin delivery: Development, in vitro characterisation and investigation of toxicity profile.Materials Science and Engineering C, 2014,38, 85-93.
37
Metal free Steveoselective synthesis of functionalized enamides.Organic & Biomolecular Chemistry,2014, 12, 242-6.
38
Synthesis and biological evaluation of substituted N-alkylphenyl-3,5-dinitrobenzamide analogs as anti-TB agents.Medicinal Chemistry Communications, 2014,5, 521-527.
39
Quantification of anticancer polyisoprenylated benzophenones garcinol and isogarcinol using multiple reaction monitoring LC-ESI-MS-MS in ultrasound assisted extracts of Garcinia indica fruits. Journal of AOAC International, 2014, 97,1317-1322.
40
Isolation, identification and simultanoeus quantification of five major flavonoids of Epimedium elatum by High Performance Liquid Chromatography. Journal of Liquid Chromatography and related Technologies, 2014, 37, 1104-1113.
41
Retrotransposon based genetic status of North-West Himalayan Zingiber officinale revealed high heterogeneity. Journal of Plant Biochemistry and Biotechnology,2014, 23, 211-216.
42
Structural Characterisation of Bacillus subtitic membrane protein Binr: an insilico approach.Current Computer Aided Drug Design, 2014,10,226-36.
43
Pharmacokinetic study of Piperine in Wistar rats after oral and intravenous administration.International Journal of drug delivery,2014, 6, 82-87.
44
Synthesis of C-spiro glyco conjugates from sugar lactones via Zinc mediated Barbies reaction.RSC Advances ,2014 ,4(22),11023-11028.
45
Endophytic fungi found in association with Bacopa monnieri as resourceful producers of industrial enzymes and antimicrobial bioactive natural products. Brazilian Archives of Biology and Technology, 2014, 57, 714-722.
46
Vasicine as tridentate Ligand for Enantioselective addition of Diethyl Zinc to Aldehydes.Tetrahedron Letters,2014, 55, 2639–2641.
47
A novel Quinazolinone derivative induce cytochrome with interpendent apoptosis and utophagy in human leukemia MOLT-4 cells.Toxicology Reports ,2014, 1,1013–1025.
48
New Biflavonoids from the roots of Scutellaria prostrata. Fitoterapia, 2014, 28,1685-1690.
49
Identifying and Developing leadership skills for the next generation library Directors in the information environment. European Academic Research,2014, I
50
A concise synthesis of Hagen’s gland lactones.Tetrahedron Letters, 2014,55, 3610–3612.
51
Osthol and curcumin as inhibitors of human Pgp and Nor A efflux pump of Staphylococcus aureus: Reversing the resistance against frontline antibacterial drugs. Med. Chem. Commun., 2014,5, 1540-1547.
52
Synthesis and anti-proliferative activities of new derivatives of embelin. Bioorganic & Medicinal Chemistry Letters,2014, 24, 4865–4870.
53
Metal-free, ionic liquid-mediated C-C/C-N bond formation and C-C- bond cleavage: Synthesis of functionalized quinolines from anilines and aldehydes. ACS Combinatorial Science ,2014,16,624-630.
54
Cu-Benzotriazole catalyzed Electrophilic cyclization of N-Arylimines: A Methodical Tandem approach to O-protected-4-hydroxyquinazolines.RSC Adv., 2014, 4, 38375-38378.
55
Hepatoprotective activity of LC-ESI-MS standardised Iris Spuria rhizome extract on its main bioactive constituents.Phytomedicine, 2014,21,1202–1207.
56
Synthesis of heteroaryl/aryl Kojic acid conjugate as stimulator of gucose uptake by GLUT4 translocation. European Journal of Medicinal Chemistry, 2014, 85, 727–736.
57
Synthetic modification of hydroxychavicol by Mannich reaction and alkyne-Azide Cyclo addition derivatives depicting cytotoxic potential. European Journal of Medicinal Chemistry,2014, 92, 236–245.
58
Targeted drug delivery systems for pancreatic cancer. The Journal of Biomedical Nanotechnology, 2014, 10, 3462-3482.
59
Co-formulation of P-glycoprotein substrate and inhibitor in Nanocarriers: An Emerging Strategy for cancer chemotherapy.Current Cancer Drug Targets, 2014,14, 419-433.
60
Paclitaxel formulations; Challenges and Novel Delivery options. Current Drug Delivery,2014, 11,666-686.
61
Advances in p-glycoprotein based approaches for delivering anticancer drugs: pharmacokinetic perspective and clinical relevance. Expert Opinion on Drug Delivery, 2014,11,121-138.