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Dr. Sanket Kumar Shukla
Senior Technical Officer (3)
Pharmacology Division
CSIR – Indian Institute of Integrative Medicine, Canal Road, Jammu – 180001
Email: sanket[dot]shukla[at]iiim[dot]res[dot]in
Bio Sketch
Central goal of our lab is to understand the potential role of inflammation in many aspect of cancer including manipulation of inflammatory system to improve the body’s ability to fight tumors. One of ourstrategy is to explore anti-inflammatory compounds as a modern cancer therapyto target inflammation around the tumors. We are also utilizing gut microbiome modification approach for reducing inflammation in cancer as well as different metabolic diseases.
Education
| Degree | Subjects | University | Qualifying Year |
| Ph.D | Microbiology | Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS),Lucknow,U.P. | 2013 |
| M.Sc | Biotechnology | D.D.U. Gorakhpur University, U.P. | 2007 |
| B.Sc | Zoology, Botany, Chemistry | D.D.U. Gorakhpur University, U.P. | 2005 |
Position Held
| Position Held | Period | Organization |
| Senior Technical Officer (3) | 2022 to Current | CSIR-IIIM, Jammu |
| Ramanujan Fellow | 2020 to 2022 | CSIR-IIIM, Jammu |
| Postdoctral Fellow | 2015 to 2020 | Thomas Jefferson University, Philadelphia, USA |
| Postdoctral Fellow | 2013 to 2015 | University of Pennsylvania, Philadelphia, USA |
Area of Expertise
- Tumor virology and Immunotherapy.
- Dietary and microbiome modification based therapeutic approaches for cancer and Inflammatory diseases.
- Anti-cancer and anti-inflammatory potential of natural and semi-synthetic natural products.
- Confocal Microscope.
Projects
- Comprehensive analysis of niche-specific microbial dysbiosis in human diseases (MMP075203) – PI
- Fermentative production, Isolation, and structure of aglucosidase inhibitor produced by Streptomyces strain (CSPS24/RDSF/IIIM/IHP24/02) – Co-PI
- Deep ocean mission for discovery and development of novel drugs and pharmaceutics (GAP- 3180) – Member
Publications
| Authors | Title | Journal |
| Kumar D, Ahmed M, Andrabi NI, Singh CP, Saroch D, Bharitkar YP, Kour G, Madishetti S, Bhagat A, Shukla SK, Ahmed Z. | Anti-inflammatory and anti-oxidant potential of dispiro-indanedione hybrid of parthenin via regulating Nrf2 and NF-κB/MAPK pathways | European Journal of Pharmacology. 2025 (IF: 4.7) |
| Bhushan A, Ahmed M, Suresh S, Singh R, Rani D, Shukla SK, Ahmed Z, Gupta P, Phatake RS | Synthesis and anticancer evaluation of Thia-Michael addition derivatives of dehydrocostuslactone: In vitro and in silico studies. | Journal of Molecular Structure. 2025 (IF: 4.7) |
| Andrabi NI, Sarkar AR, Haq SA, Kour D, Saroch D, Shukla SK, Kumar A, Bhagat A, Ali A, Kour G, Ahmed Z. | Site-selective synthesis and pharmacological elucidation of novel semi-synthetic analogues of koenimbine as a potential anti-inflammatory agent. | International Immunopharmacology. 2024 (IF: 5.6) |
| Khurana D, Shaw AK, Sharma G, Ahmed M, Shukla SK, Soni S | Experimental investigation of photothermal conversion and thermal conductivity of broadband absorbing gold nanoblackbodies and graphene oxide nanoparticles for plasmonic photothermal cancer therapy. | International Communications in Heat and Mass Transfer. 2024 (IF: 6.4) |
| Malik S, Mintoo MJ, Reddy CN, Kumar R, Kotwal P, Bharate SB, Nandi U, Mondhe DM, Shukla SK. | In vitro and in vivo anticancer potential and molecular targets of the new colchicine analog IIIM-067. | Journal of Integrative Medicine. 2023 (IF: 4.8) |
Patents
| Inventors/Contributors | Title | Description | Year |
|
Gulshan Kumar, Shazia Choudhary, Bhupesh Kumar, Alna Martin, Yogesh Sardana, Manzoor Ahmed, Sanket Kumar Shukla, Qazi Naveed Ahmed, Ravishanker, Zabeer Ahmed |
C-17 Substituted 14-Deoxy-11, 12 Didehydroandrographolide Compund as a Potential Anti-viral Agent and Process for Preperation Thereof | IN02411089701 | 2024 |
| Rubina Chowdhary, Aminur Rahman Sarkar, Manzoor Ahmed, Ghulam Mustafa, Diljeet Kumar, Ramajayan Pandian, Sanket Kumar Shukla, Rajkishor Rai, Zabeer Ahmed | Hybrid Peptide as Anticancer research | IN202411064499 |
2024 |
Awards and Honours
- Ramanujan Fellowship- Awarded by the SERB-DST Government of India, 2019.
- Young Scientist Award from European Society of Microbiology (ESCMID), 2011.
- Gold medal for best oral paper in 6th Annual Conference of U. P. MicroconIndia, 2010.
- DBT-Junior Research Fellowship, Department of Biotechnology, Government of India, 2007.
Students
| Photo | Name | Area of Interest | Position |
 |
Manzoor Ahmed | Inflammation associated cancer. |
UGC-SRF (Co-Guide) |
 |
Ghulam Mustafa |
Focused on exploring peptides as potential anti-cancer agents, with a strong foundation in cancer biology, molecular mechanisms, and therapeutic development. |
UGC-SRF (Co-Guide) |
 |
Vishal Kumar |
He is a dedicated researcher with a strong focus on pharmacokinetics studies and cancer immunotherapy, specifically targeting head and neck squamous cell carcinoma (HNSCC). Currently, He is investigating the combinational effects of a PDE-5 inhibitor with a PD-L1 inhibitor for immunotherapy in HNSCC. |
DST INSPIRE Fellow (Co-Guide) |
 |
Roopam Singh |
Focused on exploring the interplay between Type 2 diabetes mellitus, metabolic imbalances, and myocardial dysfunction, with an emphasis on early detection, pathophysiological mechanisms, and therapeutic strategies to prevent cardiovascular complications in diabetic individuals. |
Project Associate I |
 |
Snigdha Sharma | Focused on Comprehensive analysis of niche-specific microbial dysbiosis in human diseases with a particular focus on Inflammatory Bowel Disease (IBD). | Project Associate I |
 |
Khurshed Ansari | Our work is focused on Comprehensive analysis of niche-specific microbial dysbiosis in human diseases (Microbiome-mission): WP3 (IBD). | Project Associate I |
