Nuclear Magnetic Resonance Spectrometry

Overview

Nuclear magnetic resonance (NMR) spectroscopy experiments that are used to elucidate the molecular structures of natural products are based on the application of pulse sequences precisely timed radio-frequency and magnetic-field gradient pulses (usually on the microsecond and millisecond timescale) that are designed to excite the atomic nuclei of molecules and thereby produce diagnostic signals that can be analyzed to determine the connectivity of the 1H, 13C nuclei of the molecule. Two-dimensional techniques are used to determine the structure of complicated molecules.

Presently IIIM, Jammu is equipped with three NMR instruments viz. Bruker 200MHz NMR Spectrometer, Bruker 400MHz NMR Spectrometer and Bruker 500MHz NMR Spectrometer with LC-NMR facility.