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Publications During 2013

Medicinal chemistry of dihydropyran based medium ring macrolides related to aspergillides:selective inhibition of PI3K-alpha. Journal of Medicinal Chemistry, 2013,56,6122-35.
Tandem regio- and diastereo-selective synthesis of halogenated C-vinyl glycosides from unactivated arylacetylenes.Chemical Communications201349, 11409-11411.
Direct C-2 Arylation of 7-Aza indoles: Chemoselective Access to Multiarylated Derivatives. Organic Letters, 2013, 15, 5718.
Molecular Characterization of UGT94F2 and UGT86C4, Two Glycosyltransferases from Picrorhiza kurrooa: Comparative Structural Insight and Evaluation of Substrate Recognition. PLoS ONE2013, 8,e73804.
Tubulin Inhibitors from an Endophytic Fungus isolated from Cedrus deodara. Journal of Natural Products, 2013, 76, 194-199.
Tiron and trolox potentiate the autophagic cell death induced by magnolol analog Ery5 by activation of Bax in HL-60 cells. Apoptosis, 2013, 18,605-17.
NADPH-Cytochrome P450 reductase: Molecular cloning and functional characterization of two paralogs from Withania somnifera (L.) Dunal.  PLoS ONE, 2013, 8, e57068.
Montmorillonite clay catalyzed synthesis of functionalized pyrroles through domino four-component coupling of amines, aldehydes, 1,3-dicarbonyl compounds and nitroalkanes. RSC Advances, 2013, 3, 21736-21742.
Design and synthesis of carbohydrate based medium sized sulphur containing benzannulated macrocycles; Applications of Sonogashira and Heck coupling. Tetrahedron Letters, 2013, 69, 5517-5524.
Bioconversion of sucralose-6-acetate to sucralose using immobilized microbial enzymes. Journal of Molecular Catalysis B: Enzymatic, 2013,  91, 81-86.
Modulation of LPS induced inflammatory response by Lawsonyl monocyclic terpene from the marine derived Streptomyces sp. Immunology Letters, 2013, 150, 79-86.
Anti-tubercular agents. Part 7: A new class of diarylpyrrole–oxazolidinone conjugates as antimycobacterial agents. European Journal of Medicinal Chemistry, 2013, 64: 239-251.
Iron-catalyzed Cross-Coupling of Electron-Deficient Heterocycles and Quinone with Organoboron Species via Innate C–H Functionalization: Application in Total Synthesis of Pyrazine Alkaloid Botryllazine A. The Journal of Organic Chemistry, 2013, 78, 2639–2648.
Dynamics of withanolide biosynthesis in relation to temporal expression pattern of metabolic genes in Withania somnifera (L.) Dunal: a comparative study in two morpho-chemovariants. Molecular Biology Reports, 2013, 40, 7007-7016.
Effect of N-acetyl cystein on experimentally induces hepatic prs-fibrogenic events in wistar rat.Phytomedicine, 2013 20,828-33.
Discovery of 3,3'-diindolylmethanes as potent antileishmanial agents.European Journal of Medicinal Chemistry, 2013, 63,435-43.
Concentration dependent electrospray Ionisation mass spectrometry and Tandon Mass spectrometry, studies on LE, E)-1-L5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl piperidine and its analogues. SpringerPlus, 2013, 2:427.
First method for C-devinylation of aromatic systems.Tetrahedron Letters, 2013, 54,2913–2915.
Evaluation of nutritional and antioxidant states of Lepidium labifolium Linn: A novel phytofood from Ladakh. PLoS One, 2013 8,e69112.
Comparison of SSR and Cytochrome P-450 markers for estimating genetic diversity in P-Kurrooa L. Plant systematics and evolution, 2013, 299,1637-1643.
Meridianin G and its analogs as antimalarial agents.Medicinal Chemistry Communications, 2013,4,1042-1048
Copper mediated stereoselective synthesis of C-glycosides from unactivated alkynes. Chemical Communications, 2013,49,10154-10156.
Autophagy triggered by magmolol derivative negatively regulates angiogenesis. Cell Death & Disease,2013,4,e889.
Genetic and Chemo-divergence in eighteen core collection of Zingiber officnale from North-West Himalyas. Scientia Horticulture Volume,2013,160,283–291.
2-(1-amino-4-tert-bulylcyclohexyl) acetic acid (tBu-B3,3-AC6). Acta Crystallographica Section,2013,69,o888.
Cu-Mn spinel oxide catalyzed synthesis of imidazol [1,2-a] pyridines through domino three component coupling and 5-exo-dig cyclization in water. RSC Advances, 2013, 3, 20869-20876.
Montmorillonite clay Cu (II) Catalyzed domino one-pot multicomponent synthesis of 3,5-disubstituted isoxazoles. Tetrahedron Letters, 2013, 54, 3558–3561.
Chrysomycins A-C, antileukemic naphthocoumarins from Streptomyces sporoverrucosus. RSC Advances, 2013,3, 21046-21053
Kinase inhibitors of marine origin. Chemical Reviews, 2013, 113, 6761–6815.
Ammonium chloride mediated synthesis of alkyl glycosides and evaluation of their immunomodulatory activity.RSC Advances, 2013,3, 11450-11455.
Bioactive metabolites from an endophytic Cryptosporiopsis sp. Inhabiting Clidemia hirta. Phytochemistry, 2013, 95, 291–297.
Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth. Natural Product Letters, 2013, 27, 2227-2230.
New natural compounds from Rhododendron lepidotum. Natural Product Letters,2013, 27, 2033-2038.
A new isolate from fusarium sp. For nitritase production. Applied Biochemistry & Biotechnology, 2013,171,1022-1031.
Synthesis and Biological evaluation of amino analogs of Ludartin : potent and selective cytotoxic agents. Bioorganic & Medicinal Chemistry Letters , 2013, 23, 4931–4934.
Saccharanol B, a new Cytotoxic methylated isocoumarin from Saccharomonospora azurea. Tetrahedron Letters,2013,54, 6695–6699.       
Synthesis, antiproliferative and apoptosis inducing activity of thiazolol [5,4-d] pyrimidines. European Journal of Medicinal Chemistry, 2013, 70, 864–874.
Semi-synthesis of Mallotus B from rofflenin : EV evaluation of Cytotoxicity and Apoptosis Inducing activity. Journal of Natural Products  ,2013, 76 ,1724–1730.
Osmium (VI) Catalyzed chemoselective Oxidation of Allylic and Benzylic Alcohols .Tetrahedron Letters, 2013,54, 6407–6410.
Synthesis of Carboxyl  chiral macrocyclic benzolactones through Sohogashira reaction.RSC Advances, 2013, 3 ,19899-19904.
Direct C-2 Anylation of N-methyl-7-azaindole Derivatives.Organic Letters, 2013,15(22),5718-21.
Montmorillonote clay catalyzed synthesis of functionalized Pirroles through domino four component coupling of amine, aldehydes, 1-3-dicarboxyl compounds and nitro alkanes. RSC Advances, 2013, 3, 21736-21742.
A facile approach to chiral 1,4-benzodioxane the synthesis of doxazosin, Psosympal, Piperoxan and dibozene.Tetrahedron Letters, 2013,54, 6420–6422.
Isolation, Cytotoxicity evaluation and HPLC-Quantification of the Chemical Constituents from A.amyglation Decine.Journal of Chromatography B, 2013,940,135-41.
Clay entapped Cu(OH) promoted homocoupling of aryl boronic acids, an efficient and ecofriendly protocol. Journal of Applied Catalysis A, 2013,466,60-67.
Isolation and biological evaluation of chromone alkaloid dysoline, a new regioisomer of rohitukine from Dysoxylum binectariferum. Tetrahedron Letters, 2013, 54, 7140-7143.
Pro-apoptotic properties of Parthenin analogue: a quantative structure activity relationship study. Medical Chemistry Research, 2013, 22, 2303-2311.