| Animal House | QCQA | Fermentation | cGMP | Chemistry | Genetic Resource & Agrotechnology| Plant Sciences| Herbarium| Microbial Biotechnology| PK-PD| Pharmacology | Instrumentation |
Facilitate “INVIVO and PATHOLOGICAL STUDIES” for Research &Development
Mutagenicity/ Carcinogenicity study
Rodent Carcinogenicity studies
Trainings (3,6,12 month)
Micro-processor controlled fermentation facility from lab scale to pilot scale (5-4KL capacity) with supporting down-stream processing facilities for bacterial, fungal and yeast based products
State-of–art equipment required for Microbiology, Enzymology and Bio-process development
Centrifuges ranging from laboratory to pilot scale.
Developing extract from plant material
Contract/Loan license manufacturing
Stability studies
NPC
MEDCHEM
GENETIC RESOURCE & AGROTECHNOLOGY
Agro-produces at IIIM farms at Jammu/Srinagar
Plants available in plant gene banks at IIIM Srinagar Field stations
PLANT SCIENCES
PLANT BIOTECHNOLOGY
Plant Identification and Certification
Supply of Planting Materials for Research
Crude drug identification and Certification
Voucher maintenance for Herbarium samples at internationally recognized Janaki Ammal Herbarium (RRLH).
MICROBIAL BIOTECHNOLOGY
CLINICAL MICROBIOLOGY
Minimum inhibitory concentration (MIC) determination against Gram positive and Gram negative bacteria
MIC determination against yeast and fungi
MIC determination against Mycobacterium tuberculosis
In-vivo efficacy in systemic infection of model of S aureus and MRSA in mice (ED50 determination)
In-vivo efficacy in intranasal infection model of M tuberculosis in mice ( Log CFU estimation in lungs)
In-vivo efficacy in aerosol chronic infection model of M tuberculosis in mice ( Log CFU estimation in lungs)
BIOTECHNOLOGY
Molecular characterization of microbes.
Detection of following pathogens in Food and water.
Pharmacokinetics study of new chemical entities/drugs (Non-GLP)
Bioanalytical method development and validation study
Pharmacodynamics study in mice/rat (Non-GLP)
Toxicity study in mice and rat (Non-GLP)
Genotoxicity study
Reproductive toxicity study
Prenatal Developmental study
Evaluation of haematological and biochemical parameters for any animal study.
Safety pharmacology study in
Cardiovascular system (ECG, BP, Respiratory rate)
Central nervous system (Hot plate method, spontaneous motor activity, convulsion activity, pentobarbitone induced sleeping time, effect on body temperature).
Gastro-intestinal system (Charcoal meal test, bile secretion)
Physicochemical parameters determination (Solubility, LogP, LogD, PKa)
Preclinical formulation development for oral and intravenous administration
Cell based assays
PCR based assays
Cell based flocytometric assays
Autophagy detection assays
Electrophoretic assays
Enzyme based assays
In vivo anticancer assays
Fluorescence and Electron microscopic studies
ELISA based assays
MDR anticancer studies
Separation of compounds, Qualitative and quantitative analysis and Purity profile
Analysis of volatile and aromatic compounds
Characterisation of compounds
Optical studies
Freeze drying of aqueous extracts
Cryopreservation
IIIM-TBI one month training programme on cGMP
IIIM-TBI training programme on Industrial Biotechnology & Fermentation Technology
IIIM-TBI three months training programme on cGMP
Training Programme on Principle and applications of HPLC