DRUGS AND PHARMACEUTICALS


Laboratory: INDIAN INSTITUTE OF INTEGRATIVE MEDICINE, JAMMU
Facility: Testing
Discipline(s):   Chemical

S.No.

Product(s)/ Material of test

Specific tests performed

*Test Method/
Standard against which tests are performed

Range of testing/ Limits of detection

Uncertainty of  Measurement
(±)
1

Chemistry manufacturing Control (CMC) of herbal drugs

Chemical identification by spectroscopic and or chromatographic fingerprinting Assay of active constituents or characteristic markers

HPLC Profile
LCMSMS profile

 

HPTLC profile &

Quantitative
Quantitative

Qualitative confirmations

  

Toxic metals

 

 

  

Mercury

 

 DOP-104
14/12/2010
AOAC 2005 Method 990.08/
993.14 18th Ed.

0.001 to 1000 mg/kg

0.0022 at (250 mg/kg)

Lead

 

0.0001 to 1000 mg/kg

0.0011 at (250mg/kg)

Cadmium

 

0.0001 to 1000 mg/kg

0.0006 at (250 mg/kg)

Arsenic

 

0.0001 to 1000  mg/kg

 0.0012 at (250mg/kg)

Pesticides

As per Annexure -1

 

  

Toxic metals

 

 

  

Mercury

 DOP-104
14/12/2010
AOAC 2005 Method 990.08/
993.14 18th Ed.

0.001 to 1000 mg/kg

0.0022 at (250 mg/kg)

Lead

0.0001 to 1000 mg/kg

0.0011 at (250mg/kg)

Cadmium

 

0.0001 to 1000 mg/kg

0.0006 at (250 mg/kg)

Arsenic

0.0001 to 1000  mg/kg

 0.0012 at (250mg/kg)

Pesticides

As per Annexure -1

 

  

 Adventitious toxins (e.g. aflatoxin)

DOP/SOP No. 02
(AOAC 2005 18th Ed. Official
Method  990.33 Section 49.2.17)

 

  

B1

0.5-500 mg/kg

 0.549 at (20 mg/kg)

G1

0.5-500 mg/kg

 0.804 at (20 mg/kg)

G2

501-2000 mg/kg

 0.429 at (20 mg/kg)

G2

501-2000 mg/kg

 0.464 at (20 mg/kg)

Solvents

USP- 467

1 to 5000 mg/l

 

 

 

  

Methylene chloride

 0.500 (at 50mg/l)

Chloroform

 0.603 (at 50mg/l)

Methanol

 0.635 (at 50mg/l)

Hexane

 0.679 (at 50mg/l)

Carbentetra chloride

 0.831 (at 50mg/l)

Acetonitrile

 0.827 (at 50mg/l)

1,2-dimethoxy ethane

 1.274 (at 50mg/l)

Nitronmethane

 0.845 (at 50mg/l)

1,4-dioxane

 0.751 (at 50mg/l)

Methyle cyero hexane

 0.684 (at 50mg/l)

Cyclohexane

 0.246 (at 50mg/l)

Benzene

 0.165 (at 50mg/l)

Pyridine

 0.201 (at 50mg/l)

Toluene

 0.827 (at 50mg/l)

Chlorobenzene

 0.232 (at 50mg/l)

Ethylene glycol

 0.782 (at 50mg/l)

N-N’-dimethyl-acetanide

 0.429 (at 50mg/l)

Xylene

 0.827 (at 50mg/l)

Sulfolane

 0.697 (at 50mg/l)

Formanide

 0.827 (at 50mg/l)

Tetraline

 0.281 (at 50mg/l)

1-methyl-2-pyrrdidinone

 0.831 (at 50mg/l)

2-Methoxy-ethanol

 0.639 (at 50mg/l)

2-Ethoxy-ethanol

 0.550 (at 50mg/l)

Residue on ignition/ /

DOP/SOP No. 64
14/12/2010

3-25%

 0.006 at (12.25%)

water content

IS:7874 part 1 1975

0.05 to 20%

 0.045 at (10.96%)

2.0

Herbal extracts

HPLC Profile
and
HPTLC profile

DOP/SOP No. 36
Dt: 14/12/2010

Qualitative
confirmation  by comparison with the extracts of plants available/ documented in IIIM repository

 NA

2.1

Podophyllotoxins/
P. hexandrum

Assay, HPLC,

DOP/SOP No. 93
Dt: 14/12/2010

0.5 -90.0%

0.715 at (70.0%)

HPTLC profile (qualitative)

Qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000 mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg /kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250 mg/kg)

2.2

Vanillin/Vanilla parifolia

Assay, HPLC,

DOP/SOP No. 94
Dt: 14/12/2010

0.5 -90.0%

0.715 at (70.0%)

HPTLC profile (qualitative)

Qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg /kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250 mg/kg)

2.3

Saffron/ Crocus/ Preparation
E1% at 440 nm            
   1CM

Water & Volatile matter at 103oC%

DOP/SOP No. 50
Dt: 14/12/2010

IS 5453: 1996 Part 2
ISO 3632-2 : 1993

0.01-10%

 0.002 at(0.03%)

Crude fibre

0.01-10%

 0.190 at (7.9%)

Ash

0.01-10%

 0.006 at (12.25%)

Ash insoluble in HCl

0.01-10%

 0.008 at (2.5%)

Nitrogen

0.01-10%

 0.383 at (3.5%)

Colouring power

1.0-250 E1% at 440 nm        1CM

 0.022 at (250 E1% at 440 nm        1CM

2.4

Curcumin/Haldi/ Curcuma/
Preparations

Extractive value

DOP/SOP No. 61
Dt: 14/12/2010

 

0.5 -20.0%

0.041 at (11.90%)

Assay, HPLC,

0.01-99.5%

0.182 at (15.20%)

HPTLC profile

0.01-99.5%

 0.131 at (15.20%)

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250 mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

0.0012 at (250

mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

0.017 at(3.50%)

2.5

Gallic  acid /  Ellagic acid in Amalki / Terminalia /
Preparations

Extractive value

DOP/SOP No. 62
Dt: 14/12/2010

 

0.5 -30.0%

0.041 at (13.80%)

Assay, HPLC
(Gallic acid)

0.01-99.5%

0.174 at (4.25%)

Assay,HPLC
(Ellagic acid)

0.01-99.5%

 0.894 at (5.45%)

HPTLC profile
(Gallic acid)

0.01-99.5%

 0.144 at (4.25%)

HPTLC profile
(Ellagic  acid)

0.01-99.5%

 0.162 at(5.45%)

Heavy /Trace metals Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000 mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000 mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000 mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006at (12.25%)

Acid insoluble ash

2-20%

 0.017at (3.50%)

2.6

Piperine / Pimpali / Maricha / Piper preparations

Extractive value

 

 

 

 

 

DOP/SOP No. 63
Dt: 14/12/2010

 

0.5 - 25%

0.041 at (10.2%)

Assay, HPLC,

0.01-99.5%

0.348 at (14.4%)

HPTLC profile

0.01- 99.5%

 0.125 at (14.4%)

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000 mg/kg

 0.0011 at (250 mg/kg)

Cd,

0.0001-1000 mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000 mg/kg

 0.0012 at (250 mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at(20mg/kg)

B2

0.5 -500mg/kg

 0.804 at(20mg/kg)

G1

501- 2000mg/kg

 0.429 at(20mg/kg)

G2

501- 2000mg/kg

 0.464 at(20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at(3.50%)

2.7

Withanolids / Ashwangdha / withania preparations

Extractive value

DOP/SOP No. 64
Dt: 14/12/2010

0.01-99.5%

0.041 at (15.20%)

Assay, HPLC,  Withanolide A

0.01-99.5%

0.894  at (2.30%)

Assay, HPLC  Withanone

0.01-99.5%

 0.849 at (11.50%)

Assay, HPLC  Withferin A

0.01-99.5%          

0.715 at (7.50%)

HPTLC profile Withanolide A

0.01-99.5%

 0.150 at (2.30%)

HPTLC profile Withanone

0.01-99.5%

 0.867 at (11.50%)

HPTLC profile Withferin A

0.01-99.5%

 0.431 at (7.50%)

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250 mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250 mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at(20mg/kg)

B2

0.5 -500mg/kg

 0.804 at(20mg/kg)

G1

501- 2000mg/kg

 0.429 at(20mg/kg)

G2

501- 2000mg/kg

 0.464 at(20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

0.017 at (3.50%)

2.8

Pinitol / Gokhru/Tribulus preparations

 

 

 

 

 

DOP/SOP No. 65
Dt: 14/12/2010

 

 

  

HPTLC profile (qualitative)

Qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250 mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

2.9

Tinosporasides & cordiosides / Columbin edysteroids/ Guddchi / Tinospora preparations

Extractive value

 

 

 

 

 

DOP/SOP No. 66
Dt: 14/1/2/2010

 

0.5-30%

0.041 at (12.2%)

Assay, HPLC, cordiosides

0.01-10,000 mg/kg

 0.626 at (100 mg/kg)

Assay, HPLC, columbin

0.01-10,000 mg/kg

 0.268 at (100 mg/kg)

Assay, HPLC,Edysteroids

0.01-10,000 mg/kg

 0.849 at (100 mg/kg)

Assay, HPLC Tinosporasides

0.01-10,000 mg/kg

 0.357 at (100 mg/kg)

HPTLC profile Tinosporasides

0.01-10,000 mg/kg

 0.150  at (100 mg/kg)

HPTLC profile cordiosides

0.01-10,000 mg/kg

 0.304 at (100 mg/kg)

HPTLC profile columbin

0.01-10,000 mg/kg

 0.553 at (100 mg/kg)

HPTLC profile Edysteroids

0.01-10,000 mg/kg

 0.209 at (100 mg/kg)

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at(20mg/kg)

B2

0.5 -500mg/kg

 0.804 at(20mg/kg)

G1

501- 2000mg/kg

 0.429 20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)
   

Acid insoluble ash

 

2-20%

 0.017 at (3.50%)

2.10

Boswellic acids/ Salai guggal / Boswellia preparations

 

 

DOP/SOP No. 67
Dt: 14/12/2010

 

  

Extractive value

0.5 - 20%

0.041 at (10.27%)

Assay, HPLC, Boswellic acid

0.01-10,000 mg/kg

 0.534 at (100 mg/kg)

Assay, HPLC, β-Boswellic acid

0.01-10,000mg/kg

 0.697 at (100 mg/kg)

Assay, HPLC, 11-keto- β- Boswellic acid

0.01-10,000mg/kg

 0.849 at (100 mg/kg)

Acetyl 11-keto- β- Boswellic acid

0.01-10,000mg/kg

 0.581at (100 mg/kg)

β- Boswellic diol

0.01-10,000mg/kg

 0.536 at (100 mg/kg)

Acetyl  β- Boswellic acid

0.01-10,000mg/kg

 0.894 at (100 mg/kg)

HPTLC profile (Qualitative)

-

  

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.11

Shatvarin-4/ Shatavarin SafedMusali/ Asparagus preparations

Assay, HPLC,

 

DOP/SOP No. 68
Dt: 14/12/2010

 

 

0.01-10,000 mg/kg

 0.402 at (100 mg/kg)

HPTLC profile (qualitative)

Qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

 

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at 12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.12

Andrographolides/Andrographis/ preparations

Assay, HPLC,

 

DOP/SOP No. 69
Dt: 14/12/2010

 

 

0.01-10,000 mg/kg

 0.223 at (100 mg/kg)

HPTLC profile(qualitative)

qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at 12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

Assay, HPLC,

0.01-10,000 mg/kg

 0.223 at (100 mg/kg)

2.13

Gugglusterone / Commiphora/ preparations

Assay, HPLC,

DOP/SOP No. 70
Dt: 14/12/2010

 

0.01-10,000 mg/kg

 0.402 at (100 mg/kg)

HPTLC profile(qualitative)

qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

Assay, HPLC,

0.01-10,000 mg/kg

 0.402 at (100 mg/kg)

2.14

Agnuside / negundoside / Vitex / preparations

Assay, HPLC,

DOP/SOP No. 71
Dt:14/12/2010

 

 

0.01-10,000 mg/kg

 0.268 at (100 mg/kg

HPTLC profile(qualitative)

qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.15

Stevioside./ rebaudoside /  Stevia/ preparations

Assay, HPLC,

DOP/SOP No. 72
Dt: 14/12/2010

 

 

 

 

 

0.01-10,000 mg/kg

 0.402 at (100 mg/kg)

HPTLC profile

0.01-99.5%

 0.533603

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.16

Acteoside / Colebrrokia / Herbs / Preparations

Assay, HPLC,

DOP/SOP No. 73
Dt: 14/12/2010

 

 

 

 

 

0.01-10,000 mg/kg

 0.357at (100 mg/kg)

HPTLC profile(qualitative)

qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.17

Butrins / Butea/ Preparations

Assay, HPLC,

DOP/SOP No. 74
Dt: 14/12/2010

 

 

 

 

 

0.01-10,000 mg/kg

 0.357 at (100 mg/kg)

HPTLC profile(qualitative)

Qualitative

N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.18

Picrosides / Picrorhiza / Preparations

Assay, HPLC,

DOP/SOPNo. 75
Dt: 14/12/2010

0.01-10,000 mg/kg

 0.223 at (100 mg/kg)

HPTLC profile

0.01-99.5%

0.760341at 100%

HPTLC profile

0.01-99.5%

 0.112252

Heavy/Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

Assay, HPLC,

0.01-10,000 mg/kg

 0.223 at (100 mg/kg)

2.19

Catechin :
Green tea/
Accacia preprataiton

Assay, HPLC,

DOP/SOPNo. 76
Dt: 14/12/2010

 

0.01-10,000 mg/kg

 0.402 at (100 mg/kg)

HPTLC profile

0.001-1000mg/kg

 0.223 at (100 mg/kg)

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.20

10-deacetyl baccatin-III / Taxus / preparations

Assay, HPLC,

DOP/SOP No. 77
Dt: 14/12/2010

 

0.01-10,000 mg/kg

 0.536 at (100 mg/kg)

HPTLC profile (qualitative)

qualitative

 N.A.

Heavy/Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at(12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.21

Bacosides / Bacopa / Preparations

 

Assay, HPLC,

DOP/SOP No. 78
Dt: 14/12/2010

 

 

0.01-10,000 mg/kg

 0.581 at (100 mg/kg)

HPTLC profile (qualitative)

qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

2.22

Carvone/
Flavonoid glycosides in Zeera / Kalazeera / herbals / preparations

GC(Carvone)

DOP/SOP No. 79
Dt: 14/12/2010

 

0.01-10,000 mg/kg

 0.894 at (100 mg/kg)

HPTLC profile
Flavonoids

0.01-10,000 mg/kg

 0.122 at (100 mg/kg)

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

            2.23

Plumierise / Plumieria / Preparations

Assay, HPLC,

 

 

 

 

 

DOP/SOP No. 80

 

0.01-10,000 mg/kg

 0.402 at (100 mg/kg)

HPTLC profile
(qualitative)

qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006

Acid insoluble ash

2-20%

 0.0172

2.24

Amarogentin / Amarosewrin / Swertia / Preparations

 

 

 

 

 

DOP/SOP No. 81

 

 

  

Assay, HPLC,

0.01-10,000 mg/kg

 0.357 at (100 mg/kg)

HPTLC profile
(qualitative)

qualitative

 N.A.

Heavy /Trace metals
Hg

 

0.001-1000mg/kg

 0.0022 at (250 mg/kg)

Pb

0.0001-1000mg/kg

 0.0011 at (250mg/kg)

Cd,

0.0001-1000mg/kg

 0.0006 at (250 mg/kg)

As

0.0001-1000mg/kg

 0.0012 at (250mg/kg)

Aflatoxins
B1

 

0.5 -500mg/kg

 0.549 at (20mg/kg)

B2

0.5 -500mg/kg

 0.804 at (20mg/kg)

G1

501- 2000mg/kg

 0.429 at (20mg/kg)

G2

501- 2000mg/kg

 0.464 at (20mg/kg)

Total Ash

3-25%

 0.006 at (12.25%)

Acid insoluble ash

2-20%

 0.017 at (3.50%)

3.

Arka

 

 

 

  

3.1

 Pudina Arka

GC Profile:
l-Limonene
menthone
isomenthone
menthyl acetate
l- Menthol

 

 

DOP/SOP No. 12

 

 

0.5  to 70.0%

0.232 at (3.87%)
0.103 at (18.63%)
0.144 at (16.64%)
0.144 at (4.5%)

0.008 at (34.44%)

Sp. Gravity

IS: 3752 :2005

0.7  to 1.5

 0.009 at (0.95)

3.2

 

Yawani arka
(Ajwain Ark)

 

GC Profile:
g-Terpinene
p-Cymene
Thymol

DOP/SOP No. 12

 

0.5 to 7.0%
0.5 to 20%
0.5 to 70%

0.273  at (3.17 %)
0.090 at (17.59%)

0.094 at (64.01%)

Sp. Gravity

IS: 3752 :2005

0.7 to 1.5

 0.009 at (0.95)