Nuclear magnetic resonance (NMR) spectroscopy experiments
that are used to elucidate the molecular structures of
natural products are based on the application of pulse
sequences precisely timed radio-frequency and magnetic-field
gradient pulses (usually on the microsecond and millisecond
timescale) that are designed to excite the atomic nuclei
of molecules and thereby produce diagnostic signals that
can be analyzed to determine the connectivity of the 1H,
13C nuclei of the molecule. Two-dimensional techniques
are used to determine the structure of complicated molecules.
Presently IIIM, Jammu is equipped with three NMR instruments viz. Bruker 200MHz NMR Spectrometer, Bruker 400MHz NMR Spectrometer and Bruker 500MHz NMR Spectrometer with LC-NMR facility. |